Chronic Nicotine Exposure Alters Uninjured Tendon Vascularity and Viscoelasticity
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چکیده
منابع مشابه
Developmental nicotine exposure alters neurotransmission and excitability in hypoglossal motoneurons.
Hypoglossal motoneurons (XII MNs) control muscles of the mammalian tongue and are rhythmically active during breathing. Acetylcholine (ACh) modulates XII MN activity by promoting the release of glutamate from neurons that express nicotinic ACh receptors (nAChRs). Chronic nicotine exposure alters nAChRs on neurons throughout the brain, including brain stem respiratory neurons. Here we test the h...
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BACKGROUND Unaided attempts to quit smoking commonly fail during the first 2 weeks of the nicotine withdrawal syndrome. Alterations in dopamine (DA) signaling correlate with withdrawal from chronic nicotine exposure, but those changes have not been well-characterized. METHODS Mice were administered nicotine in their drinking water for 4 or 12 weeks. Then nicotine was withheld for 1 to 10 days...
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The first goal of this study was to determine whether chronic injection of nicotine alters endothelium-dependent arteriolar dilatation. We measured the diameter of cheek pouch resistance arterioles (approximately 50 microm in diameter) in response to endothelium-dependent (acetylcholine and ADP) and -independent (nitroglycerin) agonists in control hamsters and hamsters treated with nicotine (2 ...
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Paternal environmental conditions can influence phenotypes in future generations, but it is unclear whether offspring phenotypes represent specific responses to particular aspects of the paternal exposure history, or a generic response to paternal 'quality of life'. Here, we establish a paternal effect model based on nicotine exposure in mice, enabling pharmacological interrogation of the speci...
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Previous perfusion studies of the rotator cuff have demonstrated an area of bypovascularity in the distal part of the supraspinatus tendon. This has been implicated in the pathogenesis ofits rupture. We performed a quantitative histological analysis of the vascularity of the tendons ofsupraspinatus and infraspinatus. Vessel number, size and the percentage of the tendon occupied by vessels were ...
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ژورنال
عنوان ژورنال: Foot & Ankle Orthopaedics
سال: 2019
ISSN: 2473-0114,2473-0114
DOI: 10.1177/2473011419842529